Land Magnetic Observations, 1905-1910

Dmd059121 1890..1905

Subcutaneous injection is an important route of administration for therapeutic proteins that provides several advantages over other modes of parenteral delivery. Despite extensive clinical use, the exact mechanism underlying subcutaneous absorption of proteins is not completely understood, and the accuracy of prediction of absorption of biotherapeutics in humans remains unsatisfactory. This rev...

Morphological Transformation in Borrelia burgdorferi and Other Spirochetes: Observations of Round Forms & Blebs, 1905-2010

1. Al-Robaly S; 2010 Metamorphosis of Borrelia burgdorferi organisms RNA, lipid and protein composition J Basic Microbio, Oct 21. (Epub) Dihazi, H; Kacza J; in context with the spirochetes' shape. Seeger, J; Schiller, J; Huster, D; Knauer, J; Borrelia burgdorferi, the agent of Lyme borreliosis, has the ability to undergo morphological transformation Straubinger, RK. from a motile spirochetal to...

Dmd065763 1905..1916

Montelukast has been recommended as a selective in vitro and in vivo probe of cytochrome P450 (P450) CYP2C8 activity, but its selectivity toward this enzyme remains unclear. We performed detailed characterization of montelukast metabolism in vitro using human liver microsomes (HLMs), expressed P450s, and uridine 59-diphospho-glucuronosyltransferases (UGTs). Kinetic and inhibition experiments pe...

Phoebus A. Levene, 1905

Observations of Solar Coronal Magnetic

This review discusses methods for determining solar coro-nal magnetic elds, with an emphasis on radio measurements of eld strengths in solar active regions.